Loratadine CAS 79794-75-5

Product Description:

Product Name: Loratadine CAS NO: 79794-75-5

Synonyms:

Ethyl4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)p-iperidine-1-carboxylate;

Clarityn;

Lisino;

Chemical & Physical Properties:

Appearance: White powder

Assay :≥99.00%

Density: 1.261 g/cm3

Boiling Point: 531.3℃ at 760 mmHg

Melting Point: 134-136℃

Flash Point: 275.1℃

Stability: Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.

Storage Condition: 2-8℃

Water Solubility: It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.

Safety Information:

Safety Statements: S22-S24/25

HS Code: 2933990090

WGK Germany: 2

Risk Statements: R36/37/38

Hazard Code: Xi

Loratadine is a second-generation peripheral histamine H1-receptor blocker used to treat allergies. In structure, it is closely related to tricyclic antidepressants, such as imipramine, and is distantly related to the atypical antipsychotic quetiapine.

Loratadine was discovered in 1981 and came to market in 1993. It is on the World Health Organization's Model List of Essential Medicines, the most important medications needed in a basic health system. It is available as a generic drug and is marketed for its nonsedating properties. There is a version combined with pseudoephedrine, a decongestant; known as pseudoephedrine/loratadine.

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