Lisinopril CAS 76547-98-3

Product Description:

Product Name: Lisinopril CAS NO: 76547-98-3

Synonyms:

N-[(1S)-1-Carboxy-3-phenylpropyl]-L-lysyl-L-proline;

L-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-;

(2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid;

Chemical & Physical Properties:

Appearance: Solid

Assay :≥99.00%

Density: 1.3±0.1 g/cm3

Boiling Point: 666.4±55.0℃ at 760 mmHg

Flash Point: 356.9±31.5℃

Vapour Pressure: 0.0±2.1 mmHg at 25℃

Index of Refraction: 1.578

Storage Condition: 2-8℃

Water Solubility: H2O: ≥10 mg/mL

Safety Information:

Signal Word: Warning     

Precautionary Statements: P305+P351+P338        

Hazard Statements: H302-H319

Lisinopril is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.Target: ACELisinopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Lisinopril may be used to treat hypertension and symptomatic congestive heart failure, to improve survival in certain individuals following myocardial infarction, and to prevent progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy [1, 2].

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