Cetrorelix Acetate CAS 120287-85-6

Product Description:

Product Name: Cetrorelix acetate CAS NO: 120287-85-6

Synonyms:

N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2;

Ac-DNal-DpCl-Phe-DPal-Ser-Tyr-DCit-Leu-Arg-Pro-D-Ala-NH2;

Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2;

Chemical & Physical Properties:

Appearance: White powder

Assay :≥99.00%

Density: 1.42g/cm3

Refractive Index: 1.667

Long term storage: -20 ± 5℃

Safety Information:

Hazard Statements: H360

Precautionary Statements: P201,P202,P280,P308+P313,P405,P501

Cetrorelix acetate (INN, USAN, BAN) (trade name Cetrotide) is an injectable gonadotropin-releasing hormone (GnRH) antagonist. A synthetic decapeptide, it is used is used in assisted reproduction to inhibit premature luteinizing hormone surges The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In addition, cetrorelix can be used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). It is administered as either multiple 0.25mg daily subcutaneous injections or as a single-dose 3mg subcutaneous injection. The duration of the 3mg single dose is four days; if hCG is not administered within four days, a daily 0.25mg dose is started and continued until hCG is administered.

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