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Home > products > Chemical Intermediates > Regorafenib (Hydrochloride) CAS 835621-07-3

Regorafenib (Hydrochloride) CAS 835621-07-3

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 835621-07-3

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Packaging Details: Aluminum Foil Bag, Drum

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Highlight:
CAS NO::
835621-07-3
Appearance::
White To Off-white Solid
Molecular Formula::
C21H16Cl2F4N4O3
Molecular Weight::
519.27600
EINECS NO::
692-722-3
MDL NO::
MFCD22417053
CAS NO::
835621-07-3
Appearance::
White To Off-white Solid
Molecular Formula::
C21H16Cl2F4N4O3
Molecular Weight::
519.27600
EINECS NO::
692-722-3
MDL NO::
MFCD22417053
Regorafenib (Hydrochloride) CAS 835621-07-3

Product Description:

Product Name: Regorafenib (Hydrochloride) CAS NO: 835621-07-3


Synonyms:

BAY73-4506 hydrochloride;

2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1);

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide hydrochloride;


Chemical & Physical Properties:

Appearance: White to off-white solid

Assay :≥99.00%


BAY 73-4506 (Regorafenib) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.


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