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Home > products > API Active Pharmaceutical Ingredient > Ambrisentan CAS 177036-94-1 API Active Pharmaceutical Ingredient

Ambrisentan CAS 177036-94-1 API Active Pharmaceutical Ingredient

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 177036-94-1

Payment & Shipping Terms

Minimum Order Quantity: Negotiation

Price: Negotiation

Packaging Details: Aluminum Foil Bag, Drum

Delivery Time: 7-15DAY

Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram

Supply Ability: G,KG,TON

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API Ambrisentan

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Ambrisentan CAS 177036-94-1

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CAS 177036-94-1

CAS NO::
177036-94-1
Appearance::
White To Off-white Solid
Molecular Formula::
C22H22N2O4
Molecular Weight::
378.42100
EINECS NO::
658-059-9
MDL NO::
MFCD09842330
CAS NO::
177036-94-1
Appearance::
White To Off-white Solid
Molecular Formula::
C22H22N2O4
Molecular Weight::
378.42100
EINECS NO::
658-059-9
MDL NO::
MFCD09842330
Ambrisentan CAS 177036-94-1 API Active Pharmaceutical Ingredient

Product Description:

Product Name: Ambrisentan CAS NO: 177036-94-1


Synonyms:

Letairis;

(S)-2-(4,6-Dimethylpyrimidin-2-yloxy)-3-m-ethoxy-3,3-diphenylpropanoic acid;

Ambrisentan;

 

Chemical & Physical Properties:

Appearance: White to off-white solid

Assay :≥99.00%

Density: 1.228g/cm3

Boiling Point: 551.1℃ at 760mmHg

Flash Point: 287.1℃

Refractive Index: 1.593

Vapor Pressure: 5.56E-13mmHg at 25℃


Safety Information:

HS Code: 2933599090

Risk Statements: R62/63

Safety Statements: S53-36/37/39-45

RTECS : UA2459660


Endothelin -1 (ET-1) is an effective autocrine and paracrine peptide. Two receptor subtypes (ETA and ETB) co-modulate the role of ET-1 in vascular smooth muscle and endothelial cells. The main functions of ETA are vasoconstriction and cell proliferation, while the main functions of ETB are vasodilation, inhibition of proliferation, and clearance of ET-1.


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