Valsartan CAS 137862-53-4

Product Description:

Product Name: Valsartan CAS NO: 137862-53-4  

Synonyms:

N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine;

(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid;

L-Valsartan;

Chemical & Physical Properties:

Appearance: White crystalline powder

Assay :≥99.00%

Density: 1.212g/cm3

Boiling Point: 684.9℃ at 760 mmHg

Melting Point: 116-117℃

Flash Point: 368℃

Refractive Index: 1.586

Water Solubility: 84.99mg/L(25℃)

Storage Condition: Store in original container in a cool dark place.

Vapor Pressure: 1.06E-19mmHg at 25℃

Safety Information:

Safety Statements: S26; S37/39

HS Code: 2933990090

WGK Germany: 3

Risk Statements: R36/37/38

Hazard Code: Xi

Valsartan (trade name Diovan) is an angiotensin II receptor antagonist (commonly called an ARB, or angiotensin receptor blocker), that is selective for the type I (AT1) angiotensin receptor. Valsartan is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack.

Valsartan is a type of specific angiotensin I (AT1) receptor antagonist and a clinical non-dermal AT1 receptor antagonist following losartan that has important effects in adjusting bodily blood pressure and maintaining electrolyte-body fluid balance. Valsartan’s antihypertensive effects are stronger than those of enalapril and is suitable for treating hypertension, mild to moderate primary hypertension, and especially secondary hypertension caused by renal damage. It can significantly reduce proteinuria for hypertension patients with diabetes or normal liver functions, and it can promote uric acid and urinary sodium to protect the kidney. Valsartan is also suitable for reducing the cardiovascular mortality for high risk patients (left ventricular failure or dysfunction) after experiencing a heart attack.

If you are interested in our products or have any questions, please feel free to contact us!

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.