Prostaglandin E1 CAS 745-65-3

Product Description:

Product Name: Prostaglandin E1 CAS NO: 745-65-3            

Synonyms:

Prost-13-en-1-oicacid, 11,15-dihydroxy-9-oxo-, (11a,13E,15S)-;

(8S,11S,12S,13E,15R)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid;

ent-PGE1;

Chemical & Physical Properties:

Appearance: White to off-white crystalline powder

Assay :≥99.00%

Density: 1.131 g/cm3

Boiling Point: 529.3℃ at 760 mmHg

Melting Point: 115-116℃

Flash Point: 288℃

Water Solubility: Insoluble

Stability: Stable under normal temperatures and pressures

Storage Condition: -20℃

Safety Information:

Hazard Class: 6.1(b)

Safety Statement: S36

HS Code: 29375000

WGK Germany: 3

Packing Group: III

RIDADR: UN 2811

Risk Statement: R22

Hazard Codes: Xn,Xi

Prostaglandin E1 (PGE1) is a prostaglandin.The synthetic variant is known pharmaceutically as alprostadil. It is a drug used in the continuous treatment of erectile dysfunction and has vasodilatory properties. Misoprostol is another synthetic prostaglandin E1 analog used to prevent gastric ulcers when taken on a continuous basis, to treat missed miscarriage, to induce labor, and to induce abortion.

Used for diabetic neuropathy, myocardial infarction, thrombotic vasculitis, arteriosclerosis obliterans, central retinal vein thrombosis.

It is used in the treatment of hepatitis cirrhosis, cerebral infarction, diabetes, impotence, respiratory diseases. Liver damage is not serious childA, class B patients, especially patients with antithrombin level childA China effect. For induction of labor, oxytocin, renal insufficiency, treatment mumps, pancreatitis. Injection of prostaglandin E1 is mainly applied to myocardial infarction, heart failure, thrombotic vasculitis, chronic arterial occlusive disease, central retinal vein thrombosis, platelet protection for extracorporeal circulation, arteriography, revascularization surgery.

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