Abacavir CAS 136470-78-5

Product Description:

Product Name: Abacavir CAS NO: 136470-78-5       

Synonyms:

(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;

2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-;

(+/-)-4-[2-amino-6-(cyclopropylamino)-9h-purin-9-yl]-2-cyclopentene-1-methanol;

Chemical & Physical Properties:

Appearance: White powder

Assay :≥99.00%

Density: 1.7g/cm3

Boiling Point: 636℃ at 760 mmHg

Flash Point: 338.4℃

Refractive Index: 1.864

Vapor Pressure: 4.77E-17mmHg at 25℃

Storage Temp.: Refrigerator

Safety Information:

RTECS: TE3850000

Hazard Class: 6.1(b)

Safety Statements: S36/37; S45; S60; S61

Packing Group: III

RIDADR: UN 2810

Risk Statements: R21; R23/25; R43; R50/53

Hazard Codes: T; N

Abacavir (ABC) is an antiretroviral medication used to prevent and treat HIV/AIDS. Viral strains that are resistant to zidovudine (AZT) or lamivudine (3TC) are generally, but not always, sensitive to abacavir.It is well tolerated: the main side effect is hypersensitivity, which can be severe, and in rare cases, fatal. Genetic testing can indicate whether an individual is likely to be hypersensitive; over 90% of people can safely take abacavir. It is of the nucleoside analog reverse transcriptase inhibitor (NRTI) type and is in the class of carbocyclic nucleosides.

It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. It is available in the combination formulations abacavir/lamivudine/zidovudine, abacavir/dolutegravir/lamivudine, and abacavir/lamivudine. As of 2015 the cost for a typical month of medication in the United States is more than 200 USD.

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