Idebenone CAS 58186-27-9 for Skin Care and Anti-Aging Solution

Product Description:

Product Name: Idebenone CAS NO: 58186-27-9                                        

Synonyms:

2,3-d-imethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone;

2-(10-hydroxydecyl)-5,6-d-imethoxy-3-methylbenzo-1,4-quinone;

Idebenonum [Latin];

Chemical & Physical Properties:

Appearance: Yellow-orange crystalline powder

Assay :≥99.0%

Density: 1.08 g/cm3

Boiling Point: 497.3℃ at 760 mmHg

Melting Point: 52-550℃

Flash Point: 170.1℃

Refractive Index: 1.502

Stability: Stable at normal temperatures and pressures

Storage Condition: Room temp

Safety Information:

RTECS: GU5290000

Hazard Code: Xi

WGK Germany: 3

Idebenone (trade names Catena, Raxone, Sovrima, among others) is a drug that was initially developed by Takeda Pharmaceutical Company for the treatment of Alzheimer's disease and other cognitive defects. This has been met with limited success. The Swiss company Santhera Pharmaceuticals has started to investigate it for the treatment of neuromuscular diseases. In 2010, early clinical trials for the treatment of Friedreich's ataxia and Duchenne muscular dystrophy have been completed. As of December 2013[update] the drug is not approved for these indications in North America or Europe, but it is approved for the treatment of Leber's hereditary optic neuropathy (LHON) in Europe.Chemically, idebenone is an organic compound of the quinone family. It is also promoted commercially as a synthetic analog of coenzyme Q10 (CoQ10).

Idebenone is an anti-oxidant capable of protecting the skin from a variety of free-radical attacks, including the formation of secondary chemicals that negatively affect skin physiology. It is said to improve intrinsic as well as extrinsic skin damage caused by freeradical formation. Idebenone is a synthetically manufactured form of coenzyme Q10 and has a smaller molecular structure. This allows it to penetrate the skin and apparently the cellular membrane. Clinical studies demonstrate a visible improvement in photodamaged skin, reduced skin roughness and dryness, decreased fine lines and wrinkles, and increased skin hydration. In addition, idebenone helps improve hyperpigmentation because its molecular structure is similar to that of hydroquinone. Although most of the associated benefits are seen primarily in the epidermis, some increase in dermal collagen has also been confirmed. Idebenone has been used for such health-related problems as Alzheimer’s and heart disease.

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